I'm 2 weeks post op from my RYGB...I'm still on a pretty high dose of Effexor (450mg) which I believe is keeping depression mostly at bay (so far)...but I have felt melancholy at times when I let myself think about the foreverness of this change...as my therapist said, 'don't spend too much time having funerals in your mind for all the food/meals you won't be able to eat' - which is exactly what I have to be alert about... it's easy to watch a show and think "he just had 2 salted caramel chocolate cupcakes - I won't be able to do that any more'... or "wow that pizza and those fries look great, too bad I can't indulge or have a cheat day where I could stuff my face with them"... and so on... BUT I'm really trying to nip that negative, self-pitying thought train in the bud and focus on the good things to come with the weight loss and health benefits I'll have going forward...