I was only taking thyroid hormone so that was easily adjusted with a few months of blood draws. But you should ask your doc, because this is a real concern and nothing to mess with.
Check with your phar.icist. they're best Ble to tell you. I hVe 3 crush able and 2 capsules, so imlucky. The Dr said it would be trickier if I had a.xr drug (extended rease)